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Archives of Aesthetic Plastic Surgery 2012;18(3):133-137.
Published online October 31, 2012.
Application of Newly Developed Acellular Dermal Matrix Allograft (CG DermTM) in Breast Reconstruction with the Implant: The Prospective Study.
Young Seok Kim, Bo Rham Jeong, Jong Won Hong, Tai Suk Roh, Dong Kyun Rah
Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Several freeze-dried human acellular dermal matrix have been introduced and they helped to facilitate implant based breast reconstruction by providing support to the breast lower pole, firm fixation of inframammary fold, and simple operation procedure. We evaluated clinical outcomes of recently produced human acellular dermal matrix, CG Derm(TM), prospectively. CG Derm(TM) was used in six patients and eight breasts for implant breast reconstruction. Complete blood cell count test, rountine chemisty(including ESR) test, and CRP test were performed before and after the surgery. Postoperative complication was evaluated including infection, seroma, implant malpostion, rippling deformity, and capsular contracture. Randomly selected two patients underwent breast MRI after reconstruction. Finally we examine patients' satisfaction survey and plastic surgeons' evaluation. Satisfactory breast lower pole fullness, symmetric inframammary folds and breast shapes were achieved in most patients. Overall, patients had sufficient aesthetic satisfaction and surgeon's evaluation was also good. There was no major complication except four cases of seroma which healed with conservative management. Implant breast reconstruction using CG Derm(TM) was safe and obtain good aesthetic results. But further and larger scale study should be performed to reveal out the relatively high risk of seroma.
Key Words: Breast reconstruction, Breast implant, Allograft, Skin substitutes

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