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Archives of Aesthetic Plastic Surgery 2012;18(2):111-114.
Published online June 30, 2012.
Chronic Ulcerating Lesions due to Limited Form of Wegener's Granulomatosis on the Face: Cosmetic Consideration.
Seung Han Song, Soon Je Kim, Joo Hak Kim, Nak Heon Kang
Department of Plastic & Reconstructive Surgery, College of Medicine, Chungnam National University, Daejeon, Korea. nhk488@yahoo.com
Abstract
Wegener's granulomatosis (WG) is a systemic disease characterized by necrotizing granulomas and vasculitis involving the upper and lower respiratory tract as well as the kidneys. Limited form of WG usually involves the head and neck, lacks renal involvement, and may not progress to generalized disease. We report the case of limited form of WG who presented not systemic symptom but several times relapsed multiple ulcerating lesions on the face, uveitis and keratoconjunctivitis. A 23 year-old female initially presented with ulcerative skin lesions on the left cheek and nose. The skin lesion had commenced as an ulcerative and nodulopapular lesion on her right cheek initially, 8 months ago. Subsequently, there was progression of the disease to her left cheek and nose. The patient was treated with oral prednisolone and oral cyclophosphamide. Two weeks later, skin lesion had started to heal, oral prednisolone tapered to 15 mg. Eight weeks later, all of skin lesions were healed well. With silicone gel sheets and Laser therapies, we gained excellent cosmetic results. In the aesthetic aspect, early recognition of rare variants of limited form of WG, facial chronic ulcerative wounds that are nonresponsive to conservative treatment, is very important as appropriate therapy can prevent facial mutilation.
Key Words: Wegener granulomatosis, Uveitis, Keratoconjunctivitis
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